Characterization of the conditioned taste aversion produced by 7-OH-DPAT in rats.

TitleCharacterization of the conditioned taste aversion produced by 7-OH-DPAT in rats.
Publication TypeJournal Article
Year of Publication1996
JournalPharmacology, biochemistry, and behavior
Volume53
Issue3
Pagination695-9
ISSN0091-3057
Abstract

Using the conditioned taste aversion preparation, we described the dose-effect curve for the reputed dopamine D3 agonist (+/-)7-OH-DPAT (0, 0.001, 0.01, 0.1, 1.0, or 10 mg/kg). Rats received a 0.1% saccharin taste paired on repeated occasions with one of the 7-OH-DPAT doses. The 0.1, 1.0, and 10.0 mg/kg doses of 7-OH-DPAT produced a significant conditioned saccharin aversion. This aversion was evident regardless of whether saccharin intake of 7-OH-DPAT-treated rats was compared to their own water consumption or to saccharin intake by saline-treated rats.

URLhttp://linkinghub.elsevier.com/retrieve/pii/0091-3057(95)02071-3
Short TitlePharmacol Biochem Behav
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