Effects of environmental enrichment on self-administration of the short-acting opioid remifentanil in male rats.

TitleEffects of environmental enrichment on self-administration of the short-acting opioid remifentanil in male rats.
Publication TypeJournal Article
Year of Publication2017
JournalPsychopharmacology
Volume234
Issue23-24
Pagination3499-3506
ISSN0033-3158
Abstract

Opioid abuse is a major problem around the world. Identifying environmental factors that contribute to opioid abuse and addiction is necessary for decreasing this epidemic. In rodents, environmental enrichment protects against the development of low dose stimulant self-administration, but studies examining the effect of enrichment and isolation (compared to standard housing) on the development of intravenous opioid self-administration have not been conducted. The present study investigated the role of environmental enrichment on self-administration of the short-acting μ-opioid remifentanil.

URLhttps://dx.doi.org/10.1007/s00213-017-4734-2
DOI10.1007/s00213-017-4734-2
Short TitlePsychopharmacology (Berl)
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