Environmental enrichment decreases intravenous amphetamine self-administration in rats: dose-response functions for fixed- and progressive-ratio schedules.

TitleEnvironmental enrichment decreases intravenous amphetamine self-administration in rats: dose-response functions for fixed- and progressive-ratio schedules.
Publication TypeJournal Article
Year of Publication2002
JournalPsychopharmacology
Volume162
Issue4
Pagination373-8
ISSN0033-3158
Abstract

Although environmental enrichment renders rats more sensitive to the neurobehavioral effects of acute amphetamine, a previous study found that enriched rats self-administer less amphetamine than isolated rats at a low unit dose (0.03 mg/kg per infusion). In that study, however, acquisition of self-administration was limited to only two amphetamine unit doses using a fixed ratio (FR) schedule.

URLhttps://dx.doi.org/10.1007/s00213-002-1134-y
DOI10.1007/s00213-002-1134-y
Short TitlePsychopharmacology (Berl)
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