Intraindividual variability in cortisol: Approaches, illustrations, and recommendations.

TitleIntraindividual variability in cortisol: Approaches, illustrations, and recommendations.
Publication TypeJournal Article
Year of Publication2017
JournalPsychoneuroendocrinology
Volume78
Pagination114-124
ISSN0306-4530
Abstract

Most of the variance in diurnal cortisol is attributable to intraindividual variability (IIV), defined as relatively short-term, reversible changes. Multiple methods for measuring IIV have been proposed, and some have already been applied to cortisol IIV. In the present review, measurement methods are described and applied to simulated cortisol data with known underlying differences in IIV and to real cortisol data from first-year law students. More slope variance and more residual or net variance were well captured by their individual standard deviations. Explorations of reliability suggested that 10 slopes and 50 residuals result in reliable and stable estimates of the individual standard deviations. A data-analytic plan for cortisol IIV is provided.

URLhttp://linkinghub.elsevier.com/retrieve/pii/S0306-4530(16)30732-6
DOI10.1016/j.psyneuen.2017.01.026
Short TitlePsychoneuroendocrinology
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