Intramuscular Route of Administration Increases Potency in Eliciting Cocaine-Induced Behavioral Sensitization.

TitleIntramuscular Route of Administration Increases Potency in Eliciting Cocaine-Induced Behavioral Sensitization.
Publication TypeJournal Article
JournalCurrent psychopharmacology
Volume6
Issue1
Pagination36-42
Date Published2017
ISSN2211-5560
Abstract

Cocaine is the number one abused psychostimulant drug that reaches addiction criterion in the US. In animals, repeated administration of cocaine results in behavioral sensitization which is thought to represent adaptations in the mesolimbic dopamine neural circuitry, the reward pathway. Cocaine-induced behavioral sensitization is evident in rodents and quail when cocaine is administered intraperitoneally (IP).

DOI10.2174/2211556005666160902170354
Short TitleCurr Psychopharmacol
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