Optimistic expectancies and cell-mediated immunity: the role of positive affect.

TitleOptimistic expectancies and cell-mediated immunity: the role of positive affect.
Publication TypeJournal Article
Year of Publication2010
JournalPsychological science
Volume21
Issue3
Pagination448-55
ISSN0956-7976
Abstract

Optimistic expectancies affect many psychosocial outcomes and may also predict immune system changes and health, but the nature and mechanisms of any such physiological effects have not been identified. The present study related law-school expectancies to cell-mediated immunity (CMI), examining the within- and between-person components of this relationship and affective mediators. First-year law students (N = 124) completed questionnaire measures of expectancies and affect and received delayed-type hypersensitivity skin tests at five time points. A positive relationship between optimistic expectancies and CMI occurred: Changes in optimism correlated with changes in CMI. Likewise, changes in optimism predicted changes in positive and, to a lesser degree, negative affect, but the relationship between optimism and immunity was partially accounted for only by positive affect. This dynamic relationship between expectancies and immunity has positive implications for psychological interventions to improve health, particularly those that increase positive affect.

URLhttp://journals.sagepub.com/doi/abs/10.1177/0956797610362061?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
DOI10.1177/0956797610362061
Short TitlePsychol Sci
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