Rearing environment differentially modulates cocaine self-administration after opioid pretreatment: A behavioral economic analysis.

TitleRearing environment differentially modulates cocaine self-administration after opioid pretreatment: A behavioral economic analysis.
Publication TypeJournal Article
Year of Publication2016
JournalDrug and alcohol dependence
Volume167
Pagination89-94
Date Published2016
ISSN0376-8716
Abstract

Research has shown that previous experiences during development, especially if stressful, can alter an organism's response to opioids later in life. Given the previous literature on opioid modulation of cocaine self-administration, the current study raised rats in either an enriched condition (EC) or isolated condition (IC) and employed behavioral economics to study the effects of naltrexone and morphine on cocaine self-administration.

URLhttps://linkinghub.elsevier.com/retrieve/pii/S0376-8716(16)30225-3
DOI10.1016/j.drugalcdep.2016.07.026
Short TitleDrug Alcohol Depend
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