Charles Carlson

ccarl's picture
Graduate Training: 
Ph.D. Vanderbilt Univ., 1983
Research: 

My current work focuses on the application of self-regulation strategies for the management of physical disorders involving regions of the body innervated by the trigeminal nerve. The broad, long-term objective of my research program has been to understand the linkages between emotional states and physical health.  My early research career focused on exploring the influence of positive emotion, or happiness, on social behavior and perceptual processes.  Later, my clinical interests in emotional dysregulation and its effects on physical health were the impetus for my research with relaxation and other self-regulation strategies for the management of chronic pains.

Our clinical research with persons reporting pain in trigeminally-mediated regions of the body has focused on the delivery of physical self-regulation strategies targeting the control of fatigue, pain, and anxiety.  We have developed a keen interest in using heart rate variability as an index of dysregulation in these patients.   Our central hypothesis is that orofacial pain patients are not able to inhibit activation well and thus are prone to fatigue and pain.  We continue to examine the self-regulation approaches that our program has developed to improve inhibitory controls.

For the past six years I have also been developing a research program that explores the role of religiosity and spirituality in underage drinking, drug usage, and risky sexual behavior.  My research team has published a series of papers examining these issues along with developing a model to guide the development and implementation of preventive interventions.  Our goal is to foster the self-regulatory capacity of young persons so that negative outcomes from risky behavior are reduced.

In summary, my research has been directed at the interface between self-regulation, emotional processes, and health.  Our studies have contributed to a growing data base establishing the mechanisms and outcomes of the self-regulation-emotion-health linkage.  My primary research objective over the next five years is to continue systematic exploration of the psychological and physiological parameters associated with the development and treatment of pain disorders in regions of the body influenced by the trigeminal nerve.  I also will continue to develop and evaluate models guiding self-regulatory interventions directed at underage alcohol use.

Click here for information on SPRIG: Spirituality and Psychology Research Interest Group.

Selected Publications: 
  • Carlson, C. R., Reid, K. I., Curran, S. L., Studts, J., Okeson, J. P., Falace, D., Nitz, A., Bertrand, P. M. (1998). Psychological and physiological parameters of masticatory muscle pain.  Pain, 76, 297-307.
  • Carlson, C. R., Bertrand, P. M., Ehrlich, A. D., Maxwell, A. W., Burton, R. G. (2001).  Physical self-regulation training for the management of temporomandibular disorders.  Journal of Orofacial Pain, 15, 47-55.
  • Venable, V. L., Carlson, C. R., Wilson, J. (2001).  The role of anger and depression in recurrent headache.  Headache, 41, 21-30.
  • Yatani, H., Studts, J., Cordova, M., Carlson, C. R., Okeson, J.P. (2002).  Comparison of sleep quality and clinical and psychological characteristics in patients with temporomandibular disorders. Journal of Orofacial Pain, 16, 221-228.
  • de Leeuw, R., Bertoli, J., Schmidt, J., Carlson, C.R. (2005).  Prevalence of traumatic stressors in patients with temporomandibular disorders.  Journal of Oral and Maxillofacial Surgery, 63, 42-50.
  • Salsman, J. M., Carlson, C.R.  (2005).  Religious orientation, mature faith, and psychological distress:  Elements of positive and negative associations.  Journal for the Scientific Study of Religion, 44, 201-209.
  • Sherman, J.J., Carlson, C.R., Wilson, J.F., Okeson, J.P., McCubbin, J.A.  (2005).  Post-traumatic Stress Disorder among patients with orofacial pain.  Journal of Orofacial Pain, 19, 309-317.
  • Albuquerque, R.J.C., de Leeuw, R., Carlson, C.R., Okeson, J.P., Miller, C.S., Andersen, A.H. (2006).  Cerebral activation during thermal stimulation of patients who have Burning Mouth Disorder: An fMRI study.  Pain, 122, 223-234.
  • Bertoli, E., de Leeuw, R., Schmidt, J.E., Okeson, J. P., Carlson, C.R. (2007).  Prevalence and impact of post-traumatic stress disorder symptoms in patients with masticatory muscle pain and  temporomandibular joint pain:  Differences and similarities.  Journal of Orofacial Pain, 21, 1-13.
  • Brown, T.L., Salsman, J.M., Brechting, E.B., Carlson, C.R. (2007). Religiousness, spirituality, and social support: How are they related to underage drinking? Journal of Child and Adolescent Substance Abuse, 17, 15-39.
  • Carlson, C. R., (2008).  Psychological considerations for chronic orofacial pain.  Oral and Maxillofacial Surgery Clinics of North America, 20, 185-195.
  • Burris, J.L, Carlson, C.R., Smith G.T. (in press).  Relationships among religiousness, spirituality and sexual practices.  Journal of Sex Research.
  • Burris, J.L., Brechting, E., Salsman, J., Carlson, C.R. (in press).  Factors associated with the psychological well-being and distress of university students. Journal of American College Health.
  • Schmidt, J. and Carlson, C.R. (in press).   A Controlled Comparison of Emotional Reactivity and Physiological Response in Masticatory Muscle Pain Patients. Journal of Orofacial Pain.
Pubmed Publications: 
  • Finsen, A.V.;Lunde, I.G.;Sjaastad, I.;Østli, E.K.;Lyngra, M.;Jarstadmarken, H.O.;Hasic, A.;Nygård, S.;Wilcox-Adelman, S.A.;Goetinck, P.F.;Lyberg, T.;Skrbic, B.;Florholmen, G.;Tønnessen, T.;Louch, W.E.;Djurovic, S.;Carlson, C.R.;Christensen, G. "Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway." PloS one 6, 12 (2012): e28302. Details. Full text
  • Koolwal, A.B.;Barbagli, F.;Carlson, C.R.;Liang, D.H. "Catheter localization in the left atrium using an outdated anatomic reference for guidance." Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2009, (2012): 5567-70. Details. Full text
  • Sauer-Zavala, S.;Burris, J.L.;Carlson, C.R. "Understanding the Relationship Between Religiousness, Spirituality, and Underage Drinking: The Role of Positive Alcohol Expectancies." Journal of religion and health (2012): Details. Full text
  • Lunde, I.G.;Aronsen, J.M.;Kvaløy, H.;Qvigstad, E.;Sjaastad, I.;Tønnessen, T.;Christensen, G.;Grønning-Wang, L.M.;Carlson, C.R. "Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure." Physiological genomics 44, 2 (2012): 162-72. Details. Full text
  • Perez, C.V.;Leeuw, R.;Okeson, J.P.;Carlson, C.R.;Li, H.F.;Bush, H.M.;Falace, D.A. "The incidence and prevalence of temporomandibular disorders and posterior open bite in patients receiving mandibular advancement device therapy for obstructive sleep apnea." Sleep & breathing = Schlaf & Atmung (2012): Details. Full text
  • Koolwal, A.B.;Barbagli, F.;Carlson, C.R.;Liang, D.H. "An incremental method for registering electroanatomic mapping data to surface mesh models of the left atrium." Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention 11, Pt 2 (2011): 847-54. Details.
  • Wanichawan, P.;Louch, W.E.;Hortemo, K.H.;Austbø, B.;Lunde, P.K.;Scott, J.D.;Sejersted, O.M.;Carlson, C.R. "Full-length cardiac Na+/Ca2+ exchanger 1 protein is not phosphorylated by protein kinase A." American journal of physiology. Cell physiology 300, 5 (2011): C989-97. Details. Full text
  • Koolwal, A.B.;Barbagli, F.;Carlson, C.R.;Liang, D.H. "A fast slam approach to freehand 3-d ultrasound reconstruction for catheter ablation guidance in the left atrium." Ultrasound in medicine & biology 37, 12 (2011): 2037-54. Details. Full text
  • Cyders, M.A.;Burris, J.L.;Carlson, C.R. "Disaggregating the relationship between posttraumatic stress disorder symptom clusters and chronic orofacial pain: implications for the prediction of health outcomes with PTSD symptom clusters." Annals of behavioral medicine : a publication of the Society of Behavioral Medicine 41, 1 (2011): 1-12. Details. Full text
  • Lunde, I.G.;Kvaløy, H.;Austbø, B.;Christensen, G.;Carlson, C.R. "Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes." Journal of applied physiology (Bethesda, Md. : 1985) 111, 5 (2011): 1278-89. Details. Full text
  • Schmidt, J.E.;Hooten, W.M.;Carlson, C.R. "Utility of the NEO-FFI in multi-dimensional assessment of orofacial pain conditions." Journal of behavioral medicine 34, 3 (2011): 170-81. Details. Full text
  • Burris, J.L.;Evans, D.R.;Carlson, C.R. "Psychological correlates of medical comorbidities in patients with temporomandibular disorders." Journal of the American Dental Association (1939) 141, 1 (2010): 22-31. Details. Full text
  • Sauer, S.E.;Burris, J.L.;Carlson, C.R. "New directions in the management of chronic pain: self-regulation theory as a model for integrative clinical psychology practice." Clinical psychology review 30, 6 (2010): 805-14. Details. Full text
  • Røsjø, H.;Husberg, C.;Dahl, M.B.;Stridsberg, M.;Sjaastad, I.;Finsen, A.V.;Carlson, C.R.;Oie, E.;Omland, T.;Christensen, G. "Chromogranin B in heart failure: a putative cardiac biomarker expressed in the failing myocardium." Circulation. Heart failure 3, 4 (2010): 503-11. Details. Full text
  • Schmidt, J.E.;Carlson, C.R.;Usery, A.R.;Quevedo, A.S. "Effects of tongue position on mandibular muscle activity and heart rate function." Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 108, 6 (2009): 881-8. Details. Full text
  • Koolwal, A.B.;Barbagli, F.;Carlson, C.R.;Liang, D.H. "A probabilistic framework for freehand 3D ultrasound reconstruction applied to catheter ablation guidance in the left atrium." International journal of computer assisted radiology and surgery 4, 5 (2009): 425-37. Details. Full text
  • Jarnaess, E.;Stokka, A.J.;Kvissel, A.K.;Skålhegg, B.S.;Torgersen, K.M.;Scott, J.D.;Carlson, C.R.;Taskén, K. "Splicing factor arginine/serine-rich 17A (SFRS17A) is an A-kinase anchoring protein that targets protein kinase A to splicing factor compartments." The Journal of biological chemistry 284, 50 (2009): 35154-64. Details. Full text
  • Tian, G.;Granato, T.C.;Cox, A.E.;Pietz, R.I.;Carlson CR, J.;Abedin, Z. "Soil carbon sequestration resulting from long-term application of biosolids for land reclamation." Journal of environmental quality 38, 1 (1969): 61-74. Details.
  • Porto, F.;Leeuw, R.;Evans, D.R.;Carlson, C.R.;Yepes, J.F.;Branscum, A.;Okeson, J.P. "Differences in psychosocial functioning and sleep quality between idiopathic continuous orofacial neuropathic pain patients and chronic masticatory muscle pain patients." Journal of orofacial pain 25, 2 (1969): 117-24. Details.
  • Burris, J.L.;Cyders, M.A.;Leeuw, R.;Smith, G.T.;Carlson, C.R. "Posttraumatic stress disorder symptoms and chronic orofacial pain: an empirical examination of the mutual maintenance model." Journal of orofacial pain 23, 3 (1969): 243-52. Details.
  • Burris, J.L.;Brechting, E.H.;Salsman, J.;Carlson, C.R. "Factors associated with the psychological well-being and distress of university students." Journal of American college health : J of ACH 57, 5 (1969): 536-43. Details. Full text
  • Davis, C.E.;Carlson, C.R.;Studts, J.L.;Curran, S.L.;Hoyle, R.H.;Sherman, J.J.;Okeson, J.P. "Use of a structural equation model for prediction of pain symptoms in patients with orofacial pain and temporomandibular disorders." Journal of orofacial pain 24, 1 (1969): 89-100. Details.
  • Burris, J.L.;Smith, G.T.;Carlson, C.R. "Relations among religiousness, spirituality, and sexual practices." Journal of sex research 46, 4 (1969): 282-9. Details. Full text
  • Schmidt, J.E.;Carlson, C.R. "A controlled comparison of emotional reactivity and physiological response in masticatory muscle pain patients." Journal of orofacial pain 23, 3 (1969): 230-42. Details.
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