My current work focuses on the application of self-regulation strategies for the management of physical disorders involving regions of the body innervated by the trigeminal nerve. The broad, long-term objective of my research program has been to understand the linkages between emotional states and physical health. My early research career focused on exploring the influence of positive emotion, or happiness, on social behavior and perceptual processes. Later, my clinical interests in emotional dysregulation and its effects on physical health were the impetus for my research with relaxation and other self-regulation strategies for the management of chronic pains.
Our clinical research with persons reporting pain in trigeminally-mediated regions of the body has focused on the delivery of physical self-regulation strategies targeting the control of fatigue, pain, and anxiety. We have developed a keen interest in using heart rate variability as an index of dysregulation in these patients. Our central hypothesis is that orofacial pain patients are not able to inhibit activation well and thus are prone to fatigue and pain. We continue to examine the self-regulation approaches that our program has developed to improve inhibitory controls.
For the past six years I have also been developing a research program that explores the role of religiosity and spirituality in underage drinking, drug usage, and risky sexual behavior. My research team has published a series of papers examining these issues along with developing a model to guide the development and implementation of preventive interventions. Our goal is to foster the self-regulatory capacity of young persons so that negative outcomes from risky behavior are reduced.
In summary, my research has been directed at the interface between self-regulation, emotional processes, and health. Our studies have contributed to a growing data base establishing the mechanisms and outcomes of the self-regulation-emotion-health linkage. My primary research objective over the next five years is to continue systematic exploration of the psychological and physiological parameters associated with the development and treatment of pain disorders in regions of the body influenced by the trigeminal nerve. I also will continue to develop and evaluate models guiding self-regulatory interventions directed at underage alcohol use.
Click here for information on SPRIG: Spirituality and Psychology Research Interest Group.
- Carlson, C. R., Reid, K. I., Curran, S. L., Studts, J., Okeson, J. P., Falace, D., Nitz, A., Bertrand, P. M. (1998). Psychological and physiological parameters of masticatory muscle pain. Pain, 76, 297-307.
- Carlson, C. R., Bertrand, P. M., Ehrlich, A. D., Maxwell, A. W., Burton, R. G. (2001). Physical self-regulation training for the management of temporomandibular disorders. Journal of Orofacial Pain, 15, 47-55.
- Venable, V. L., Carlson, C. R., Wilson, J. (2001). The role of anger and depression in recurrent headache. Headache, 41, 21-30.
- Yatani, H., Studts, J., Cordova, M., Carlson, C. R., Okeson, J.P. (2002). Comparison of sleep quality and clinical and psychological characteristics in patients with temporomandibular disorders. Journal of Orofacial Pain, 16, 221-228.
- de Leeuw, R., Bertoli, J., Schmidt, J., Carlson, C.R. (2005). Prevalence of traumatic stressors in patients with temporomandibular disorders. Journal of Oral and Maxillofacial Surgery, 63, 42-50.
- Salsman, J. M., Carlson, C.R. (2005). Religious orientation, mature faith, and psychological distress: Elements of positive and negative associations. Journal for the Scientific Study of Religion, 44, 201-209.
- Sherman, J.J., Carlson, C.R., Wilson, J.F., Okeson, J.P., McCubbin, J.A. (2005). Post-traumatic Stress Disorder among patients with orofacial pain. Journal of Orofacial Pain, 19, 309-317.
- Albuquerque, R.J.C., de Leeuw, R., Carlson, C.R., Okeson, J.P., Miller, C.S., Andersen, A.H. (2006). Cerebral activation during thermal stimulation of patients who have Burning Mouth Disorder: An fMRI study. Pain, 122, 223-234.
- Bertoli, E., de Leeuw, R., Schmidt, J.E., Okeson, J. P., Carlson, C.R. (2007). Prevalence and impact of post-traumatic stress disorder symptoms in patients with masticatory muscle pain and temporomandibular joint pain: Differences and similarities. Journal of Orofacial Pain, 21, 1-13.
- Brown, T.L., Salsman, J.M., Brechting, E.B., Carlson, C.R. (2007). Religiousness, spirituality, and social support: How are they related to underage drinking? Journal of Child and Adolescent Substance Abuse, 17, 15-39.
- Carlson, C. R., (2008). Psychological considerations for chronic orofacial pain. Oral and Maxillofacial Surgery Clinics of North America, 20, 185-195.
- Burris, J.L, Carlson, C.R., Smith G.T. (in press). Relationships among religiousness, spirituality and sexual practices. Journal of Sex Research.
- Burris, J.L., Brechting, E., Salsman, J., Carlson, C.R. (in press). Factors associated with the psychological well-being and distress of university students. Journal of American College Health.
- Schmidt, J. and Carlson, C.R. (in press). A Controlled Comparison of Emotional Reactivity and Physiological Response in Masticatory Muscle Pain Patients. Journal of Orofacial Pain.
- "Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress." Journal of molecular and cellular cardiology 54, (2013): 73-81. Details. Full text
- "Differential regulation of extracellular matrix constituents in myocardial remodeling with and without heart failure following pressure overload." Matrix biology : journal of the International Society for Matrix Biology 32, 2 (2013): 133-42. Details. Full text
- "The incidence and prevalence of temporomandibular disorders and posterior open bite in patients receiving mandibular advancement device therapy for obstructive sleep apnea." Sleep & breathing = Schlaf & Atmung 17, 1 (2013): 323-32. Details. Full text
- "Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart." The FEBS journal 280, 10 (2013): 2228-47. Details. Full text
- "Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure." Physiological genomics 44, 2 (2012): 162-72. Details. Full text
- "Understanding the Relationship Between Religiousness, Spirituality, and Underage Drinking: The Role of Positive Alcohol Expectancies." Journal of religion and health (2012): Details. Full text
- "Disaggregating the relationship between posttraumatic stress disorder symptom clusters and chronic orofacial pain: implications for the prediction of health outcomes with PTSD symptom clusters." Annals of behavioral medicine : a publication of the Society of Behavioral Medicine 41, 1 (2011): 1-12. Details. Full text
- "Angiotensin II and norepinephrine activate specific calcineurin-dependent NFAT transcription factor isoforms in cardiomyocytes." Journal of applied physiology (Bethesda, Md. : 1985) 111, 5 (2011): 1278-89. Details. Full text
- "Utility of the NEO-FFI in multi-dimensional assessment of orofacial pain conditions." Journal of behavioral medicine 34, 3 (2011): 170-81. Details. Full text
- "A fast slam approach to freehand 3-d ultrasound reconstruction for catheter ablation guidance in the left atrium." Ultrasound in medicine & biology 37, 12 (2011): 2037-54. Details. Full text
- "Full-length cardiac Na+/Ca2+ exchanger 1 protein is not phosphorylated by protein kinase A." American journal of physiology. Cell physiology 300, 5 (2011): C989-97. Details. Full text
- "Chromogranin B in heart failure: a putative cardiac biomarker expressed in the failing myocardium." Circulation. Heart failure 3, 4 (2010): 503-11. Details. Full text
- "Psychological correlates of medical comorbidities in patients with temporomandibular disorders." Journal of the American Dental Association (1939) 141, 1 (2010): 22-31. Details. Full text
- "New directions in the management of chronic pain: self-regulation theory as a model for integrative clinical psychology practice." Clinical psychology review 30, 6 (2010): 805-14. Details. Full text
- "Effects of tongue position on mandibular muscle activity and heart rate function." Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 108, 6 (2009): 881-8. Details. Full text
- "A probabilistic framework for freehand 3D ultrasound reconstruction applied to catheter ablation guidance in the left atrium." International journal of computer assisted radiology and surgery 4, 5 (2009): 425-37. Details. Full text
- "Splicing factor arginine/serine-rich 17A (SFRS17A) is an A-kinase anchoring protein that targets protein kinase A to splicing factor compartments." The Journal of biological chemistry 284, 50 (2009): 35154-64. Details. Full text
- "Psychological considerations for chronic orofacial pain." Oral and maxillofacial surgery clinics of North America 20, 2 (2008): 185-95, vi. Details.
- "Prevalence of temporomandibular disorders in fibromyalgia and failed back syndrome patients: a blinded prospective comparison study." Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 104, 2 (2007): 204-16. Details. Full text
- "Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin." Journal of immunology (Baltimore, Md. : 1950) 179, 8 (2007): 5159-68. Details. Full text
- "Psychological factors associated with orofacial pains." Dental clinics of North America 51, 1 (2007): 145-60, vii. Details. Full text
- "AKAP complex regulates Ca2+ re-uptake into heart sarcoplasmic reticulum." EMBO reports 8, 11 (2007): 1061-7. Details. Full text
- "Molecular basis of AKAP specificity for PKA regulatory subunits." Molecular cell 24, 3 (2006): 383-95. Details. Full text
- "Delineation of type I protein kinase A-selective signaling events using an RI anchoring disruptor." The Journal of biological chemistry 281, 30 (2006): 21535-45. Details. Full text
- "Brain activity during stimulation of the trigeminal nerve with noxious heat." Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 102, 6 (2006): 750-7. Details. Full text
- "Influence of estrogen on brain activation during stimulation with painful heat." Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 64, 2 (2006): 158-66. Details. Full text
- "Characterization of A-kinase-anchoring disruptors using a solution-based assay." The Biochemical journal 400, 3 (2006): 493-9. Details. Full text
- "Cerebral activation during thermal stimulation of patients who have burning mouth disorder: an fMRI study." Pain 122, 3 (2006): 223-34. Details. Full text
- "A fast and sensitive method for isolation of detergent-resistant membranes from T cells." Journal of immunological methods 305, 2 (2005): 199-205. Details. Full text
- "Fatigue and fatigue-related symptoms in an orofacial pain population." Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 99, 2 (2005): 168-74. Details. Full text
- "Prevalence of post-traumatic stress disorder symptoms in orofacial pain patients." Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 99, 5 (2005): 558-68. Details. Full text
- "Prevalence of traumatic stressors in patients with temporomandibular disorders." Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 63, 1 (2005): 42-50. Details. Full text
- "Psychological and sleep quality differences between chronic daily headache and temporomandibular disorders patients." Cephalalgia : an international journal of headache 24, 6 (2004): 446-54. Details. Full text
- "A kinase anchoring protein (AKAP) interaction and dimerization of the RIalpha and RIbeta regulatory subunits of protein kinase a in vivo by the yeast two hybrid system." Journal of molecular biology 327, 3 (2003): 609-18. Details. Full text
- "Merlin links to the cAMP neuronal signaling pathway by anchoring the RIbeta subunit of protein kinase A." The Journal of biological chemistry 278, 42 (2003): 41167-72. Details. Full text
- "Burning mouth (syndrome) disorder." Quintessence international (Berlin, Germany : 1985) 34, 8 (2003): 587-93. Details.
- "Physical mapping of the Bacillus thuringiensis subsp. kurstaki and alesti chromosomes." Current microbiology 44, 2 (2002): 81-7. Details.
- "CDK1-mediated phosphorylation of the RIIalpha regulatory subunit of PKA works as a molecular switch that promotes dissociation of RIIalpha from centrosomes at mitosis." Journal of cell science 114, Pt 18 (2001): 3243-54. Details. Full text
- "Binding of PKA-RIIalpha to the Adenovirus E1A12S oncoprotein correlates with its nuclear translocation and an increase in PKA-dependent promoter activity." Virology 285, 1 (2001): 30-41. Details. Full text
- "Regulation of anchoring of the RIIalpha regulatory subunit of PKA to AKAP95 by threonine phosphorylation of RIIalpha: implications for chromosome dynamics at mitosis." Journal of cell science 114, Pt 18 (2001): 3255-64. Details. Full text
- "Social constraints, cognitive processing, and adjustment to breast cancer." Journal of consulting and clinical psychology 69, 4 (2001): 706-11. Details. Full text
- "The role of anger and depression in recurrent headache." Headache 41, 1 (2001): 21-30. Details. Full text
- "Posttraumatic growth following breast cancer: a controlled comparison study." Health psychology : official journal of the Division of Health Psychology, American Psychological Association 20, 3 (2001): 176-85. Details. Full text
- "A fission yeast general translation factor reveals links between protein synthesis and cell cycle controls." Journal of cell science 113 ( Pt 8), (2000): 1447-58. Details. Full text
- "Regulation of the start of DNA replication in Schizosaccharomyces pombe." Journal of cell science 112 ( Pt 6), (1999): 939-46. Details. Full text
- "Psychological and physiological parameters of masticatory muscle pain." Pain 76, 3 (1998): 297-307. Details. Full text
- "Localization of putative virulence genes on a physical map of the bacillus thuringiensis subsp. gelechiae chromosome" Current microbiology 37, 4 (1998): 245-50. Details. Full text
- "Measurement of nuclear DNA content in fission yeast by flow cytometry." Yeast (Chichester, England) 13, 14 (1997): 1329-35. Details. Full text
- "Variable numbers of rRNA gene operons in Bacillus cereus strains." FEMS microbiology letters 136, 3 (1996): 325-8. Details.
- "Relaxation training and opioid inhibition of blood pressure response to stress." Journal of consulting and clinical psychology 64, 3 (1996): 593-601. Details. Full text
- "Psychological coping with acute pain: an examination of the role of endogenous opioid mechanisms." Journal of behavioral medicine 19, 2 (1996): 129-42. Details.
- "The chromosome map of Bacillus thuringiensis subsp. canadensis HD224 is highly similar to that of the Bacillus cereus type strain ATCC 14579." FEMS microbiology letters 141, 2-3 (1996): 163-7. Details.
- "Ambulatory electromyogram activity in the upper trapezius region: patients with muscle pain vs. pain-free control subjects." Spine 21, 5 (1996): 595-9. Details. Full text
- "Influence of a sympathomimetic amine on masticatory and trapezius pain/pressure thresholds and electromyographic levels." Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 82, 5 (1996): 525-31. Details. Full text
- "Coping styles, opioid blockade, and cardiovascular response to stress." Journal of behavioral medicine 17, 1 (1994): 25-40. Details.
- "Genotypic Diversity among Bacillus cereus and Bacillus thuringiensis Strains." Applied and environmental microbiology 60, 6 (1994): 1719-25. Details. Full text
- "Stretch-based relaxation training." Patient education and counseling 23, 1 (1994): 5-12. Details.
- "A small (2.4 Mb) Bacillus cereus chromosome corresponds to a conserved region of a larger (5.3 Mb) Bacillus cereus chromosome." Molecular microbiology 13, 1 (1994): 161-9. Details. Full text
- "An unusual reaction to opioid blockade with naltrexone in a case of post-traumatic stress disorder." Journal of traumatic stress 7, 2 (1994): 303-9. Details.
- "Efficacy of abbreviated progressive muscle relaxation training: a quantitative review of behavioral medicine research." Journal of consulting and clinical psychology 61, 6 (1993): 1059-67. Details. Full text
- "A complete physical map of a Bacillus thuringiensis chromosome." Journal of bacteriology 175, 4 (1993): 1053-60. Details. Full text
- "Reduction of pain and EMG activity in the masseter region by trapezius trigger point injection." Pain 55, 3 (1993): 397-400. Details.
- "Two brief interventions for acute pain." Pain 54, 1 (1993): 29-36. Details. Full text
- "The relationship between pain sensitivity and blood pressure in normotensives." Pain 48, 3 (1992): 463-7. Details.
- "Physical maps of the genomes of three Bacillus cereus strains." Journal of bacteriology 174, 11 (1992): 3750-6. Details. Full text
- "Predisposing psychological factors in the development of reflex sympathetic dystrophy. A review of the empirical evidence." The Clinical journal of pain 8, 4 (1992): 287-99. Details.
- "Negative side effects of self-regulation training: relaxation and the role of the professional in service delivery." Biofeedback and self-regulation 16, 2 (1991): 191-7. Details.
- "Muscle stretching as an alternative relaxation training procedure." Journal of behavior therapy and experimental psychiatry 21, 1 (1990): 29-38. Details. Full text
- "Relaxation training through muscle stretching procedures: a pilot case." Journal of behavior therapy and experimental psychiatry 18, 2 (1987): 121-6. Details.
- "A behavioral intervention to increase exercise among nursing home residents." The Gerontologist 26, 5 (1986): 479-81. Details. Full text
- "Data-based versus symptomatic formulation of treatment: the case of a dependent personality." Journal of behavior therapy and experimental psychiatry 15, 2 (1984): 153-60. Details. Full text
- "An assessment of the treatment needs of Vietnam-era veterans." Hospital & community psychiatry 35, 7 (1984): 691-6. Details.
- "Theory of shape-invariant imaging systems." Journal of the Optical Society of America. A, Optics and image science 1, 10 (1984): 1040-53. Details.
- "Spatially inhomogeneous scaled transforms for vision and pattern recognition." Optics letters 6, 8 (1981): 386-8. Details.
- "Soil carbon sequestration resulting from long-term application of biosolids for land reclamation." Journal of environmental quality 38, 1 (1969): 61-74. Details.
- "Use of a structural equation model for prediction of pain symptoms in patients with orofacial pain and temporomandibular disorders." Journal of orofacial pain 24, 1 (1969): 89-100. Details.
- "Comparison of psychologic and physiologic functioning between patients with masticatory muscle pain and matched controls." Journal of orofacial pain 7, 1 (1969): 15-22. Details.
- "Effect of long-term application of biosolids for land reclamation on surface water chemistry." Journal of environmental quality 35, 1 (1969): 101-13. Details.
- "Effects of stretch-based progressive relaxation training on the secretion of salivary immunoglobulin A in orofacial pain patients." Journal of orofacial pain 11, 2 (1969): 115-24. Details.
- "Physical self-regulation training for the management of temporomandibular disorders." Journal of orofacial pain 15, 1 (1969): 47-55. Details.
- "Psychosocial profiles of patients with burning mouth syndrome." Journal of orofacial pain 14, 1 (1969): 59-64. Details.
- "Stretch-based relaxation and the reduction of EMG activity among masticatory muscle pain patients." Journal of craniomandibular disorders : facial & oral pain 5, 3 (1969): 205-12. Details.
- "A comparison between masticatory muscle pain patients and intracapsular pain patients on behavioral and psychosocial domains." Journal of orofacial pain 16, 4 (1969): 277-83. Details.
- "Factors associated with the psychological well-being and distress of university students." Journal of American college health : J of ACH 57, 5 (1969): 536-43. Details. Full text
- "Effects of long-term application of biosolids for mine land reclamation on groundwater chemistry: trace metals." Journal of environmental quality 41, 5 (1969): 1445-51. Details.
- "Post-traumatic stress disorder among patients with orofacial pain." Journal of orofacial pain 19, 4 (1969): 309-17. Details.
- "Prevalence and impact of post-traumatic stress disorder symptoms in patients with masticatory muscle or temporomandibular joint pain: differences and similarities." Journal of orofacial pain 21, 2 (1969): 107-19. Details.
- "Routine dental care in patients with temporomandibular disorders." Journal of orofacial pain 16, 2 (1969): 129-34. Details.
- "Influence of biased clinician statements on patient report of referred pain." Journal of orofacial pain 14, 2 (1969): 120-7. Details.
- "Trace element concentrations in soil, corn leaves, and grain after cessation of biosolids applications." Journal of environmental quality 33, 6 (1969): 2078-89. Details.
- "Differences in psychosocial functioning and sleep quality between idiopathic continuous orofacial neuropathic pain patients and chronic masticatory muscle pain patients." Journal of orofacial pain 25, 2 (1969): 117-24. Details.
- "Emotional and physiologic responses to laboratory challenges: patients with temporomandibular disorders versus matched control subjects." Journal of orofacial pain 10, 2 (1969): 141-50. Details.
- "Impact of criteria-based diagnosis of burning mouth syndrome on treatment outcome." Journal of orofacial pain 16, 4 (1969): 305-11. Details.
- "A controlled comparison of emotional reactivity and physiological response in masticatory muscle pain patients." Journal of orofacial pain 23, 3 (1969): 230-42. Details.
- "Traumatic stressors and post-traumatic stress disorder symptoms in headache patients." Headache 45, 10 (1969): 1365-74. Details. Full text
- "Physical and sexual abuse among orofacial pain patients: linkages with pain and psychologic distress." Journal of orofacial pain 9, 4 (1969): 340-6. Details.
- "The effects of tongue position on mandibular muscle activity." Journal of orofacial pain 11, 4 (1969): 291-7. Details.
- "The psychobiology of hostility: possible endogenous opioid mechanisms." International journal of behavioral medicine 3, 2 (0): 163-76. Details.
- "Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway." PloS one 6, 12 (0): e28302. Details. Full text
- "Visual processing of simple two-dimensional sine-wave luminance gratings." Vision research 17, 3 (0): 351-8. Details.
- "An incremental method for registering electroanatomic mapping data to surface mesh models of the left atrium." Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention 11, Pt 2 (0): 847-54. Details.
- "Visual illusions without low spatial frequencies." Vision research 24, 10 (0): 1407-13. Details. Full text
- "A large format optical display for the generation of generalized psychophysical stimuli." Vision research 19, 1 (0): 99-103. Details.
- "Catheter localization in the left atrium using an outdated anatomic reference for guidance." Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2009, (0): 5567-70. Details. Full text
- "Comparison of sleep quality and clinical and psychologic characteristics in patients with temporomandibular disorders." Journal of orofacial pain 16, 3 (0): 221-8. Details.



