Mark Prendergast

prender's picture
Research

My laboratory's research efforts are focused on examining mechanisms involved in the development of alcohol dependence and the biochemistry of brain injury resulting from exposure to:
  1.  alcohol
  2.  "stress hormones"
  3.  pesticides
  4.  psychomotor stimulants

In studying these topics, my laboratory employs a broad range of neurochemical and behavioral techniques, including cell culture of brain tissue, in vivo rodent studies, Western blot analysis and immunohistochemistry.

 

 

Graduate Training
Ph.D. Univ. of Nebraska, 1994
Selected Publications: 

     Butler TR, Smith KJ,  Self RL, Braden BB, Prendergast MA (2008). Sex differences in neurotoxic effects of adenosine A1 receptor antagonism during ethanol withdrawal in vitro: reversal with co-exposure to an A1 receptor agonist or and NMDA receptor antagonist. Alcoholism Clinical and Experimental Research, 32(7), 1260-1270.

     Self RL, Smith KJ, Butler TR, Pauly JR, Prendergast MA (2009). Intra-cornu ammonis 1 administration of the human immunodeficiency virus-1 transcription factor Tat exacerbates the ethanol withdrawal syndrome in rodents and activates N-methyl-D-aspartate glutamate receptors to produce persisting spatial learning deficits. Neuroscience, 163, 868-876.

     Butler TR, Self RL, Smith KJ, Sharrett-Field LJ, Berry JN, Littleton JM, Pauly JR, Mulholland PJ, Prendergast MA (2010). Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D-asparate-type glutamate receptors. Neuroscience165(2):525-34.

     Butler TR and Prendergast MA (In Press). Neuroadaptations in adenosine receptor signaling following long-term ethanol exposure and withdrawal. Alcoholism: Clinical and Experimental Research

     Prendergast MAand Mulholland PJ (In Press) Glucocorticoid and polyamine interactions in the plasticity of glutamatergic synapses that contribute to ethanol-associated dependence and neuronal injury. Addiction Biology

PubMed Publications*: 
  • Reynolds, AR ;Berry, JN ;Sharrett-Field, L.;Prendergast, MA "Ethanol withdrawal is required to produce persisting N-methyl-D-aspartate receptor-dependent hippocampal cytotoxicity during chronic intermittent ethanol exposure." Alcohol (Fayetteville, N.Y.) 49, 3 (2015): 219-27. Details. Full text
  • Sharrett-Field, L.;Butler, TR ;Reynolds, AR ;Berry, JN ;Prendergast, MA "Sex differences in neuroadaptation to alcohol and withdrawal neurotoxicity." Pflugers Archiv : European journal of physiology 465, 5 (2013): 643-54. Details. Full text
  • Rumbaugh, JA ;Bachani, M.;Li, W.;Butler, TR ;Smith, KJ ;Bianchet, MA ;Wang, T.;Prendergast, MA ;Sacktor, N.;Nath, A. "HIV immune complexes prevent excitotoxicity by interaction with NMDA receptors." Neurobiology of disease 49, (2013): 169-76. Details. Full text
  • Smith, KJ ;Butler, TR ;Prendergast, MA "Ethanol impairs microtubule formation via interactions at a microtubule associated protein-sensitive site." Alcohol (Fayetteville, N.Y.) 47, 7 (2013): 539-43. Details. Full text
  • Sharrett-Field, L.;Butler, TR ;Berry, JN ;Reynolds, AR ;Prendergast, MA "Mifepristone pretreatment reduces ethanol withdrawal severity in vivo." Alcoholism, clinical and experimental research 37, 8 (2013): 1417-23. Details. Full text
  • Butler, TR ;Berry, JN ;Sharrett-Field, LJ ;Pauly, JR ;Prendergast, MA "Long-term ethanol and corticosterone co-exposure sensitize the hippocampal ca1 region pyramidal cells to insult during ethanol withdrawal in an NMDA GluN2B subunit-dependent manner." Alcoholism, clinical and experimental research 37, 12 (2013): 2066-73. Details. Full text
  • Butler, TR ;Prendergast, MA "Neuroadaptations in adenosine receptor signaling following long-term ethanol exposure and withdrawal." Alcoholism, clinical and experimental research 36, 1 (2012): 4-13. Details. Full text
  • Prendergast, MA ;Mulholland, PJ "Glucocorticoid and polyamine interactions in the plasticity of glutamatergic synapses that contribute to ethanol-associated dependence and neuronal injury." Addiction biology 17, 2 (2012): 209-23. Details. Full text
  • Berry, JN ;Sharrett-Field, LJ ;Butler, TR ;Prendergast, MA "Temporal dependence of cysteine protease activation following excitotoxic hippocampal injury." Neuroscience 222, (2012): 147-58. Details. Full text
  • Thompson, DO ;Prendergast, MA ;Shockley, LW "Traumatic pneumothorax with air mimicking lung markings." The Journal of emergency medicine 43, 6 (2012): e463-4. Details. Full text
  • Rahman, S.;Prendergast, MA "Cholinergic receptor system as a target for treating alcohol abuse and dependence." Recent patents on CNS drug discovery 7, 2 (2012): 145-50. Details. Full text
  • Butler, TR ;Smith, KJ ;Self, RL ;Braden, BB ;Prendergast, MA "Neurodegenerative effects of recombinant HIV-1 Tat(1-86) are associated with inhibition of microtubule formation and oxidative stress-related reductions in microtubule-associated protein-2(a,b)." Neurochemical research 36, 5 (2011): 819-28. Details. Full text
  • Butler, TR ;Self, RL ;Smith, KJ ;Sharrett-Field, LJ ;Berry, JN ;Littleton, JM ;Pauly, JR ;Mulholland, PJ ;Prendergast, MA "Selective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D-asparate-type glutamate receptors." Neuroscience 165, 2 (2010): 525-34. Details. Full text
  • Smith, KJ ;Butler, TR ;Prendergast, MA "Inhibition of sigma-1 receptor reduces N-methyl-D-aspartate induced neuronal injury in methamphetamine-exposed and -naive hippocampi." Neuroscience letters 481, 3 (2010): 144-8. Details. Full text
  • Rose, AK ;Shaw, SG ;Prendergast, MA ;Little, HJ "The importance of glucocorticoids in alcohol dependence and neurotoxicity." Alcoholism, clinical and experimental research 34, 12 (2010): 2011-8. Details. Full text
  • Self, RL ;Smith, KJ ;Butler, TR ;Pauly, JR ;Prendergast, MA "Intra-cornu ammonis 1 administration of the human immunodeficiency virus-1 protein trans-activator of transcription exacerbates the ethanol withdrawal syndrome in rodents and activates N-methyl-D-aspartate glutamate receptors to produce persisting..." Neuroscience 163, 3 (2009): 868-76. Details. Full text
  • Butler, TR ;Smith, KJ ;Self, RL ;Braden, BB ;Prendergast, MA "Sex differences in the neurotoxic effects of adenosine A1 receptor antagonism during ethanol withdrawal: reversal with an A1 receptor agonist or an NMDA receptor antagonist." Alcoholism, clinical and experimental research 32, 7 (2008): 1260-70. Details. Full text
  • Jacquot, C.;Croft, AP ;Prendergast, MA ;Mulholland, P.;Shaw, SG ;Little, HJ "Effects of the glucocorticoid antagonist, mifepristone, on the consequences of withdrawal from long term alcohol consumption." Alcoholism, clinical and experimental research 32, 12 (2008): 2107-16. Details. Full text
  • Barron, S.;Mulholland, PJ ;Littleton, JM ;Prendergast, MA "Age and gender differences in response to neonatal ethanol withdrawal and polyamine challenge in organotypic hippocampal cultures." Alcoholism, clinical and experimental research 32, 6 (2008): 929-36. Details. Full text
  • Smith, KJ ;Butler, TR ;Self, RL ;Braden, BB ;Prendergast, MA "Potentiation of N-methyl-D-aspartate receptor-mediated neuronal injury during methamphetamine withdrawal in vitro requires co-activation of IP3 receptors." Brain research 1187, (2008): 67-73. Details. Full text
  • Smith, KJ ;Self, RL ;Butler, TR ;Mullins, MM ;Ghayoumi, L.;Holley, RC ;Littleton, JM ;Prendergast, MA "Methamphetamine exposure antagonizes N-methyl-D-aspartate receptor-mediated neurotoxicity in organotypic hippocampal slice cultures." Brain research 1157, (2007): 74-80. Details. Full text
  • Buccafusco, JJ ;Powers, JC ;Hernandez, MA ;Prendergast, MA ;Terry, AV ;Jonnala, RR "MHP-133, a drug with multiple CNS targets: potential for neuroprotection and enhanced cognition." Neurochemical research 32, 7 (2007): 1224-37. Details. Full text
  • Gearhart, DA ;Sickles, DW ;Buccafusco, JJ ;Prendergast, MA ;Terry AV, Jr "Chlorpyrifos, chlorpyrifos-oxon, and diisopropylfluorophosphate inhibit kinesin-dependent microtubule motility." Toxicology and applied pharmacology 218, 1 (2007): 20-9. Details. Full text
  • Terry AV, Jr ;Gearhart, DA ;Beck WD, Jr ;Truan, JN ;Middlemore, ML ;Williamson, LN ;Bartlett, MG ;Prendergast, MA ;Sickles, DW ;Buccafusco, JJ "Chronic, intermittent exposure to chlorpyrifos in rats: protracted effects on axonal transport, neurotrophin receptors, cholinergic markers, and information processing." The Journal of pharmacology and experimental therapeutics 322, 3 (2007): 1117-28. Details. Full text
  • Prendergast, MA ;Little, HJ "Adolescence, glucocorticoids and alcohol." Pharmacology, biochemistry, and behavior 86, 2 (2007): 234-45. Details. Full text
  • Prendergast, MA ;Self, RL ;Smith, KJ ;Ghayoumi, L.;Mullins, MM ;Butler, TR ;Buccafusco, JJ ;Gearhart, DA ;Terry AV, Jr "Microtubule-associated targets in chlorpyrifos oxon hippocampal neurotoxicity." Neuroscience 146, 1 (2007): 330-9. Details. Full text
  • Wilkins LH, Jr ;Prendergast, MA ;Blanchard, J.;Holley, RC ;Chambers, ER ;Littleton, JM "Potential value of changes in cell markers in organotypic hippocampal cultures associated with chronic EtOH exposure and withdrawal: comparison with NMDA-induced changes." Alcoholism, clinical and experimental research 30, 10 (2006): 1768-80. Details. Full text
  • Mulholland, PJ ;Self, RL ;Hensley, AK ;Little, HJ ;Littleton, JM ;Prendergast, MA "A 24 h corticosterone exposure exacerbates excitotoxic insult in rat hippocampal slice cultures independently of glucocorticoid receptor activation or protein synthesis." Brain research 1082, 1 (2006): 165-72. Details. Full text
  • Mulholland, PJ ;Self, RL ;Harris, BR ;Little, HJ ;Littleton, JM ;Prendergast, MA "Corticosterone increases damage and cytosolic calcium accumulation associated with ethanol withdrawal in rat hippocampal slice cultures." Alcoholism, clinical and experimental research 29, 5 (2005): 871-81. Details. Full text
  • Self, RL ;Smith, KJ ;Mulholland, PJ ;Prendergast, MA "Ethanol exposure and withdrawal sensitizes the rat hippocampal CA1 pyramidal cell region to beta-amyloid (25-35)-induced cytotoxicity: NMDA receptor involvement." Alcoholism, clinical and experimental research 29, 11 (2005): 2063-9. Details. Full text
  • Mulholland, PJ ;Self, RL ;Harris, BR ;Littleton, JM ;Prendergast, MA "Choline exposure reduces potentiation of N-methyl-D-aspartate toxicity by corticosterone in the developing hippocampus." Brain research. Developmental brain research 153, 2 (2004): 203-11. Details. Full text
  • Self, RL ;Mulholland, PJ ;Harris, BR ;Nath, A.;Prendergast, MA "Cytotoxic effects of exposure to the human immunodeficiency virus type 1 protein Tat in the hippocampus are enhanced by prior ethanol treatment." Alcoholism, clinical and experimental research 28, 12 (2004): 1916-24. Details. Full text
  • Self, RL ;Mulholland, PJ ;Nath, A.;Harris, BR ;Prendergast, MA "The human immunodeficiency virus type-1 transcription factor Tat produces elevations in intracellular Ca2+ that require function of an N-methyl-D-aspartate receptor polyamine-sensitive site." Brain research 995, 1 (2004): 39-45. Details. Full text
  • Mulholland, PJ ;Prendergast, MA "Transection of intrinsic polysynaptic pathways reduces N-methyl-D-aspartate neurotoxicity in hippocampal slice cultures." Neuroscience research 46, 3 (2003): 369-76. Details. Full text
  • Terry AV, Jr ;Stone, JD ;Buccafusco, JJ ;Sickles, DW ;Sood, A.;Prendergast, MA "Repeated exposures to subthreshold doses of chlorpyrifos in rats: hippocampal damage, impaired axonal transport, and deficits in spatial learning." The Journal of pharmacology and experimental therapeutics 305, 1 (2003): 375-84. Details. Full text
  • Harris, BR ;Gibson, DA ;Prendergast, MA ;Blanchard, JA ;Holley, RC ;Hart, SR ;Scotland, RL ;Foster, TC ;Pedigo, NW ;Littleton, JM "The neurotoxicity induced by ethanol withdrawal in mature organotypic hippocampal slices might involve cross-talk between metabotropic glutamate type 5 receptors and N-methyl-D-aspartate receptors." Alcoholism, clinical and experimental research 27, 11 (2003): 1724-35. Details. Full text
  • Kelly, TH ;Stoops, WW ;Perry, AS ;Prendergast, MA ;Rush, CR "Clinical neuropharmacology of drugs of abuse: a comparison of drug-discrimination and subject-report measures." Behavioral and cognitive neuroscience reviews 2, 4 (2003): 227-60. Details. Full text
  • Gibson, DA ;Harris, BR ;Prendergast, MA ;Hart, SR ;Blanchard JA, 2nd ;Holley, RC ;Pedigo, NW ;Littleton, JM "Polyamines contribute to ethanol withdrawal-induced neurotoxicity in rat hippocampal slice cultures through interactions with the NMDA receptor." Alcoholism, clinical and experimental research 27, 7 (2003): 1099-106. Details. Full text
  • Bain, JN ;Prendergast, MA ;Terry AV, Jr ;Arneric, SP ;Smith, MA ;Buccafusco, JJ "Enhanced attention in rhesus monkeys as a common factor for the cognitive effects of drugs with abuse potential." Psychopharmacology 169, 2 (2003): 150-60. Details. Full text
  • Mayer, S.;Harris, B.;Gibson, DA ;Blanchard, J.;Prendergast, MA ;Holley, RC ;Littleton, J. "Acamprosate has no effect on NMDA-induced toxicity but reduces toxicity induced by spermidine or by changing the medium in organotypic hippocampal slice cultures from rat." Alcoholism, clinical and experimental research 26, 5 (2002): 655-62. Details. Full text
  • Harris, BR ;Prendergast, MA ;Gibson, DA ;Rogers, DT ;Blanchard, JA ;Holley, RC ;Fu, MC ;Hart, SR ;Pedigo, NW ;Littleton, JM "Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors." Alcoholism, clinical and experimental research 26, 12 (2002): 1779-93. Details. Full text
  • Mayer, S.;Harris, BR ;Gibson, DA ;Blanchard, JA ;Prendergast, MA ;Holley, RC ;Littleton, J. "Acamprosate, MK-801, and ifenprodil inhibit neurotoxicity and calcium entry induced by ethanol withdrawal in organotypic slice cultures from neonatal rat hippocampus." Alcoholism, clinical and experimental research 26, 10 (2002): 1468-78. Details. Full text
  • Mulholland, PJ ;Prendergast, MA "Post-insult exposure to (+/-) kavain potentiates N-methyl-D-aspartate toxicity in the developing hippocampus." Brain research 945, 1 (2002): 106-13. Details. Full text
  • Prendergast, MA ;Rogers, DT ;Mulholland, PJ ;Littleton, JM ;Wilkins LH, Jr ;Self, RL ;Nath, A. "Neurotoxic effects of the human immunodeficiency virus type-1 transcription factor Tat require function of a polyamine sensitive-site on the N-methyl-D-aspartate receptor." Brain research 954, 2 (2002): 300-7. Details. Full text
  • Prendergast, MA ;Yells, DP ;Balogh, SE ;Paige, SR ;Hendricks, SE "Fluoxetine differentially suppresses sucrose solution consumption in free-fed and food-deprived rats--reversal by amantadine." Medical science monitor : international medical journal of experimental and clinical research 8, 10 (2002): BR385-90. Details. Full text
  • Prendergast, MA ;Harris, BR ;Mayer, S.;Littleton, JM "Chronic, but not acute, nicotine exposure attenuates ethanol withdrawal-induced hippocampal damage in vitro." Alcoholism, clinical and experimental research 24, 10 (2000): 1583-92. Details. Full text
  • Stone, JD ;Terry AV, Jr ;Pauly, JR ;Prendergast, MA ;Buccafusco, JJ "Protractive effects of chronic treatment with an acutely sub-toxic regimen of diisopropylflurophosphate on the expression of cholinergic receptor densities in rats." Brain research 882, 1-2 (2000): 9-18. Details. Full text
  • Prendergast, MA ;Harris, BR ;Blanchard JA, 2nd ;Mayer, S.;Gibson, DA ;Littleton, JM "In vitro effects of ethanol withdrawal and spermidine on viability of hippocampus from male and female rat." Alcoholism, clinical and experimental research 24, 12 (2000): 1855-61. Details. Full text
  • Prendergast, MA ;Jackson, WJ ;Terry AV, Jr ;Decker, MW ;Arneric, SP ;Buccafusco, JJ "Central nicotinic receptor agonists ABT-418, ABT-089, and (-)-nicotine reduce distractibility in adult monkeys." Psychopharmacology 136, 1 (1998): 50-8. Details. Full text
  • Prendergast, MA ;Buccafusco, JJ "(-)-Nicotine increases mRNA encoding G3PDH and the vesicular acetylcholine transporter in vivo." Neuroreport 9, 7 (1998): 1385-9. Details. Full text
  • Terry AV, Jr ;Buccafusco, JJ ;Jackson, WJ ;Prendergast, MA ;Fontana, DJ ;Wong, EH ;Bonhaus, DW ;Weller, P.;Eglen, RM "Enhanced delayed matching performance in younger and older macaques administered the 5-HT4 receptor agonist, RS 17017." Psychopharmacology 135, 4 (1998): 407-15. Details. Full text
  • Prendergast, MA ;Jackson, WJ ;Terry AV, Jr ;Kille, NJ ;Arneric, SP ;Decker, MW ;Buccafusco, JJ "Age-related differences in distractibility and response to methylphenidate in monkeys." Cerebral cortex (New York, N.Y. : 1991) 8, 2 (1998): 164-72. Details. Full text
  • Prendergast, MA ;Terry AV, Jr ;Buccafusco, JJ "Chronic, low-level exposure to diisopropylfluorophosphate causes protracted impairment of spatial navigation learning." Psychopharmacology 129, 2 (1997): 183-91. Details. Full text
  • Decker, MW ;Bannon, AW ;Curzon, P.;Gunther, KL ;Brioni, JD ;Holladay, MW ;Lin, NH ;Li, Y.;Daanen, JF ;Buccafusco, JJ ;Prendergast, MA ;Jackson, WJ ;Arneric, SP "ABT-089 2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride : II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys." The Journal of pharmacology and experimental therapeutics 283, 1 (1997): 247-58. Details. Full text
  • Lin, NH ;Gunn, DE ;Ryther, KB ;Garvey, DS ;Donnelly-Roberts, DL ;Decker, MW ;Brioni, JD ;Buckley, MJ ;Rodrigues, AD ;Marsh, KG ;Anderson, DJ ;Buccafusco, JJ ;Prendergast, MA ;Sullivan, JP ;Williams, M.;Arneric, SP ;Holladay, MW "Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties." Journal of medicinal chemistry 40, 3 (1997): 385-90. Details. Full text
  • Prendergast, MA ;Terry AV, Jr ;Jackson, WJ ;Buccafusco, JJ "Nitric oxide synthase inhibition impairs delayed recall in mature monkeys." Pharmacology, biochemistry, and behavior 56, 1 (1997): 81-7. Details. Full text
  • Prendergast, MA ;Terry AV, Jr ;Jackson, WJ ;Marsh, KC ;Decker, MW ;Arneric, SP ;Buccafusco, JJ "Improvement in accuracy of delayed recall in aged and non-aged, mature monkeys after intramuscular or transdermal administration of the CNS nicotinic receptor agonist ABT-418." Psychopharmacology 130, 3 (1997): 276-84. Details. Full text
  • Terry AV, Jr ;Buccafusco, JJ ;Prendergast, MA ;Jackson, WJ ;Fontana, DL ;Wong, EH ;Whiting, RL ;Eglen, RM "The 5-HT3 receptor antagonist, RS-56812, enhances delayed matching performance in monkeys." Neuroreport 8, 1 (1996): 49-54. Details. Full text
  • Prendergast, MA ;Hendricks, SE ;Yells, DP ;Balogh, S. "Conditioned taste aversion induced by fluoxetine." Physiology & behavior 60, 1 (1996): 311-5. Details. Full text
  • Yells, DP ;Prendergast, MA ;Hendricks, SE ;Miller, ME "Monoaminergic influences on temporal patterning of sexual behavior in male rats." Physiology & behavior 58, 5 (1995): 847-52. Details. Full text
  • Yells, DP ;Prendergast, MA ;Hendricks, SE ;Nakamura, M. "Fluoxetine-induced inhibition of male rat copulatory behavior: modification by lesions of the nucleus paragigantocellularis." Pharmacology, biochemistry, and behavior 49, 1 (1994): 121-7. Details. Full text
  • Yells, DP ;Hendricks, SE ;Prendergast, MA "Lesions of the nucleus paragigantocellularis: effects on mating behavior in male rats." Brain research 596, 1-2 (1992): 73-9. Details. Full text
  • Mulholland, PJ ;Harris, BR ;Wilkins, LH ;Self, RL ;Blanchard, JA ;Holley, RC ;Littleton, JM ;Prendergast, MA "Opposing effects of ethanol and nicotine on hippocampal calbindin-D28k expression." Alcohol (Fayetteville, N.Y.) 31, 1-2 (1969): 1-10. Details. Full text
  • Hart, RA ;Prendergast, MA ;Roberts, WG ;Nesbit, GM ;Barnwell, SL "Proximal junctional acute collapse cranial to multi-level lumbar fusion: a cost analysis of prophylactic vertebral augmentation." The spine journal : official journal of the North American Spine Society 8, 6 (1969): 875-81. Details. Full text
  • Devaud, LL ;Prendergast, MA "Introduction to the special issue of Alcohol and Alcoholism on sex/gender differences in responses to alcohol." Alcohol and alcoholism (Oxford, Oxfordshire) 44, 6 (1969): 533-4. Details. Full text
  • Briggs, CA ;Anderson, DJ ;Brioni, JD ;Buccafusco, JJ ;Buckley, MJ ;Campbell, JE ;Decker, MW ;Donnelly-Roberts, D.;Elliott, RL ;Gopalakrishnan, M.;Holladay, MW ;Hui, YH ;Jackson, WJ ;Kim, DJ ;Marsh, KC ;O'Neill, A.;Prendergast, MA ;Ryther, KB ;Sullivan, JP ;Arneric, SP "Functional characterization of the novel neuronal nicotinic acetylcholine receptor ligand GTS-21 in vitro and in vivo." Pharmacology, biochemistry, and behavior 57, 1-2 (1969): 231-41. Details. Full text
  • Prendergast, MA ;Terry AV, Jr ;Buccafusco, JJ "Effects of chronic, low-level organophosphate exposure on delayed recall, discrimination, and spatial learning in monkeys and rats." Neurotoxicology and teratology 20, 2 (1969): 115-22. Details. Full text
  • Clarke, MS ;Prendergast, MA ;Terry AV, Jr "Plasma membrane ordering agent pluronic F-68 (PF-68) reduces neurotransmitter uptake and release and produces learning and memory deficits in rats." Learning & memory (Cold Spring Harbor, N.Y.) 6, 6 (1969): 634-49. Details. Full text
  • Prendergast, MA ;Harris, BR ;Mayer, S.;Holley, RC ;Pauly, JR ;Littleton, JM "Nicotine exposure reduces N-methyl-D-aspartate toxicity in the hippocampus: relation to distribution of the alpha7 nicotinic acetylcholine receptor subunit." Medical science monitor : international medical journal of experimental and clinical research 7, 6 (1969): 1153-60. Details.
  • Butler, TR ;Smith, KJ ;Berry, JN ;Sharrett-Field, LJ ;Prendergast, MA "Sex differences in caffeine neurotoxicity following chronic ethanol exposure and withdrawal." Alcohol and alcoholism (Oxford, Oxfordshire) 44, 6 (1969): 567-74. Details. Full text
  • Prendergast, MA ;Buccafusco, JJ ;Terry AV, Jr "Nitric oxide synthase inhibition impairs spatial navigation learning and induces conditioned taste aversion." Pharmacology, biochemistry, and behavior 57, 1-2 (1969): 347-52. Details. Full text
  • Prendergast, MA "Do women possess a unique susceptibility to the neurotoxic effects of alcohol?" Journal of the American Medical Women's Association (1972) 59, 3 (1969): 225-7. Details.
  • Prendergast, MA ;Harris, BR ;Mullholland, PJ ;Blanchard JA, 2nd ;Gibson, DA ;Holley, RC ;Littleton, JM "Hippocampal CA1 region neurodegeneration produced by ethanol withdrawal requires activation of intrinsic polysynaptic hippocampal pathways and function of N-methyl-D-aspartate receptors." Neuroscience 124, 4 (0): 869-77. Details. Full text
  • Prendergast, MA ;Harris, BR ;Mayer, S.;Holley, RC ;Hauser, KF ;Littleton, JM "Chronic nicotine exposure reduces N-methyl-D-aspartate receptor-mediated damage in the hippocampus without altering calcium accumulation or extrusion: evidence of calbindin-D28K overexpression." Neuroscience 102, 1 (0): 75-85. Details. Full text
  • Mulholland, PJ ;Self, RL ;Harris, BR ;Littleton, JM ;Prendergast, MA "(-)-nicotine ameliorates corticosterone's potentiation of N-methyl-d-aspartate receptor-mediated cornu ammonis 1 toxicity." Neuroscience 125, 3 (0): 671-82. Details. Full text
  • Mulholland, PJ ;Self, RL ;Stepanyan, TD ;Little, HJ ;Littleton, JM ;Prendergast, MA "Thiamine deficiency in the pathogenesis of chronic ethanol-associated cerebellar damage in vitro." Neuroscience 135, 4 (0): 1129-39. Details. Full text
  • Hart, RA ;Prendergast, MA "Spine surgery for lumbar degenerative disease in elderly and osteoporotic patients." Instructional course lectures 56, (0): 257-72. Details.
  • Mulholland, PJ ;Stepanyan, TD ;Self, RL ;Hensley, AK ;Harris, BR ;Kowalski, A.;Littleton, JM ;Prendergast, MA "Corticosterone and dexamethasone potentiate cytotoxicity associated with oxygen-glucose deprivation in organotypic cerebellar slice cultures." Neuroscience 136, 1 (0): 259-67. Details. Full text
* Publications are automatically pulled from pubmed.gov based on a user-specific query. Results may include incorrect citations. See: Tutorial on improving PubMed results.
X
Enter your link blue username.
Enter your link blue password.
Secure Login

This login is SSL protected

Loading